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Activation mechanism dependent surface exposure of cellular factor XIII on activated platelets and platelet microparticles

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Platelets contain a high amount of potentially active A subunit dimer of coagulation factor XIII (cellular FXIII; cFXIII). It is of cytoplasmic localization, not secreted, but becomes translocated to the… Click to show full abstract

Platelets contain a high amount of potentially active A subunit dimer of coagulation factor XIII (cellular FXIII; cFXIII). It is of cytoplasmic localization, not secreted, but becomes translocated to the surface of platelets activated by convulxin and thrombin (CVX+Thr).

Keywords: factor xiii; mechanism dependent; surface; activation mechanism; factor

Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2022

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