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Anti‐phosphatidylserine prothrombin antibodies as a predictor of the lupus anticoagulant in an all‐comer population

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Anti‐phosphatidylserine prothrombin antibodies (aPSPT) are reported to be highly associated with the lupus anticoagulant (LAC) in established antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) cohorts. Further, aPSPT has been… Click to show full abstract

Anti‐phosphatidylserine prothrombin antibodies (aPSPT) are reported to be highly associated with the lupus anticoagulant (LAC) in established antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) cohorts. Further, aPSPT has been suggested to be a useful surrogate LAC marker. However, validation studies replicating this relationship in an all‐comer study population in the diagnostic clinical setting are lacking.

Keywords: phosphatidylserine prothrombin; lupus anticoagulant; prothrombin antibodies; anti phosphatidylserine

Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2022

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