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Platelets are affected by many factors, such as infectious or aseptic inflammation, and different inflammatory states may induce either thrombocytopenia or thrombocytosis. Tumor necrosis factor α (TNFα) is an important… Click to show full abstract
Platelets are affected by many factors, such as infectious or aseptic inflammation, and different inflammatory states may induce either thrombocytopenia or thrombocytosis. Tumor necrosis factor α (TNFα) is an important inflammatory cytokine that has been shown to affect the activity of hematopoietic stem cells. However, its role in megakaryocyte (MK) development and platelet production remains largely unknown. This study aimed to investigate the effects of TNFα on MK and platelet generation.
Keywords:
tumor necrosis;
platelet production;
necrosis factor;
inflammatory cytokine
Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2022
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Journal Title: Journal of Thrombosis and Haemostasis
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!