"Deep sequence analysis of NS5A resistance‐associated substitution changes in patients reinfected with the hepatitis C virus after liver transplantation"

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The hepatitis C virus (HCV) is an enveloped virus with a positive-senseRNA genome of ~ 9.6 kDa in length. In the body, circulating HCV genomes are highly variable due to… Click to show full abstract

The hepatitis C virus (HCV) is an enveloped virus with a positive-senseRNA genome of ~ 9.6 kDa in length. In the body, circulating HCV genomes are highly variable due to the rapidity of RNA virus evolution by error-prone RNA-dependent RNA polymerases, so they exist as quasispecies.

Keywords: sequence analysis; hepatitis virus; analysis ns5a; ns5a resistance; virus; deep sequence

Journal Title: Journal of Viral Hepatitis
Year Published: 2020

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