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Mutations in the novel gene FOPV are associated with familial autosomal dominant and non‐familial obliterative portal venopathy

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Obliterative portal venopathy (OPV) is characterized by lesions of portal vein intrahepatic branches and is thought to be responsible for many cases of portal hypertension in the absence of cirrhosis… Click to show full abstract

Obliterative portal venopathy (OPV) is characterized by lesions of portal vein intrahepatic branches and is thought to be responsible for many cases of portal hypertension in the absence of cirrhosis or obstruction of large portal or hepatic veins. In most cases the cause of OPV remains unknown. The aim was to identify a candidate gene of OPV.

Keywords: obliterative portal; portal venopathy; mutations novel; novel gene

Journal Title: Liver International
Year Published: 2018

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