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Circulating markers of gut barrier function associated with disease severity in primary sclerosing cholangitis

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One important hypothesis in primary sclerosing cholangitis pathophysiology suggests that bacterial products from an inflamed leaky gut lead to biliary inflammation. We aimed to investigate whether circulating markers of bacterial… Click to show full abstract

One important hypothesis in primary sclerosing cholangitis pathophysiology suggests that bacterial products from an inflamed leaky gut lead to biliary inflammation. We aimed to investigate whether circulating markers of bacterial translocation were associated with survival in a Norwegian primary sclerosing cholangitis cohort.

Keywords: markers gut; primary sclerosing; gut barrier; sclerosing cholangitis; circulating markers

Journal Title: Liver International
Year Published: 2019

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