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Upregulation of hepatic delta‐aminolevulinic acid synthase 1 with accumulation of potentially toxic heme precursors delta‐aminolevulinic acid and porphobilinogen is fundamental to the pathogenesis of acute hepatic porphyria. Aims: evaluate long‐term… Click to show full abstract
Upregulation of hepatic delta‐aminolevulinic acid synthase 1 with accumulation of potentially toxic heme precursors delta‐aminolevulinic acid and porphobilinogen is fundamental to the pathogenesis of acute hepatic porphyria. Aims: evaluate long‐term efficacy and safety of givosiran in acute hepatic porphyria.
Keywords:
acute hepatic;
efficacy safety;
givosiran acute;
hepatic porphyria;
safety givosiran
Journal Title: Liver International
Year Published: 2021
Link to full text (if available)
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Journal Title: Liver International
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!