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According to pivotal clinical trials, cure rates for sofosbuvir‐based antiviral therapy exceed 96%. Treatment failure is usually assumed to be because of virological resistance‐associated substitutions or clinical risk factors, yet… Click to show full abstract
According to pivotal clinical trials, cure rates for sofosbuvir‐based antiviral therapy exceed 96%. Treatment failure is usually assumed to be because of virological resistance‐associated substitutions or clinical risk factors, yet the role of patient‐specific genetic factors has not been well explored. We determined if patient‐specific genetic factors help predict patients likely to fail sofosbuvir treatment in real‐world treatment situations.
Keywords:
specific genetic;
treatment failure;
treatment;
genetic factors;
patient specific
Journal Title: Liver International
Year Published: 2022
Link to full text (if available)
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Journal Title: Liver International
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!