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Immune checkpoint inhibitors in malignancies after liver transplantation: A systematic review and pooled analysis

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Treatment of de novo malignancies and recurrent hepatocellular carcinoma with immune checkpoint inhibitors (ICI) in liver transplant recipients (LT) is an attractive strategy that is infrequently pursued because of the… Click to show full abstract

Treatment of de novo malignancies and recurrent hepatocellular carcinoma with immune checkpoint inhibitors (ICI) in liver transplant recipients (LT) is an attractive strategy that is infrequently pursued because of the lack of strong evidence regarding their safety and efficacy. In this systematic review with pooled analysis, we aimed to assess safety and efficacy of ICI therapy following LT.

Keywords: review pooled; checkpoint inhibitors; immune checkpoint; systematic review; pooled analysis

Journal Title: Liver International
Year Published: 2022

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