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Curable response to crizotinib in a patient with liver metastatic inflammatory myofibroblastic tumour carrying a TFG‐ROS1 fusion

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An 8- year- old girl presented with a 2- month history of jaundice. The physical examination revealed yellowing of the skin and sclera. Liver function tests revealed elevated direct bilirubin… Click to show full abstract

An 8- year- old girl presented with a 2- month history of jaundice. The physical examination revealed yellowing of the skin and sclera. Liver function tests revealed elevated direct bilirubin (103 μ mol/L), alkaline phosphatase (1192 IU/L), and gamma- glutamyltransferase (293 IU/L) levels. The tumour markers (alpha- fetoprotein, carci-noembryonic antigen and neuron- specific enolase) were negative.

Keywords: crizotinib patient; response crizotinib; metastatic inflammatory; curable response; patient liver; liver metastatic

Journal Title: Liver International
Year Published: 2022

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