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Serum concentration of taurochenodeoxycholic acid predicts clinically significant portal hypertension

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Severity of portal hypertension is usually quantified by measuring the hepatic venous pressure gradient (HVPG). However, due to its invasiveness, alternative markers are being sought. Bile acids (BA), being synthesized,… Click to show full abstract

Severity of portal hypertension is usually quantified by measuring the hepatic venous pressure gradient (HVPG). However, due to its invasiveness, alternative markers are being sought. Bile acids (BA), being synthesized, metabolized, and transported by the liver, seem to have the potential to serve as endogenous markers. The aim of the present study was to determine whether serum BA reflect the severity of portal hypertension.

Keywords: taurochenodeoxycholic acid; hypertension; concentration taurochenodeoxycholic; serum concentration; portal hypertension

Journal Title: Liver International
Year Published: 2022

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