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PNPLA3 I148M and response to treatment for hepatic steatosis: A systematic review

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It is unclear whether the patatin‐like phospholipase domain‐containing protein 3 (PNPLA3) rs738409 C‐to‐G single nucleotide polymorphism, resulting in the substitution of isoleucine to methionine at position 148 (I148M), impedes regression… Click to show full abstract

It is unclear whether the patatin‐like phospholipase domain‐containing protein 3 (PNPLA3) rs738409 C‐to‐G single nucleotide polymorphism, resulting in the substitution of isoleucine to methionine at position 148 (I148M), impedes regression of hepatic steatosis when treating non‐alcoholic fatty liver disease (NAFLD).

Keywords: pnpla3 i148m; pnpla3; response treatment; hepatic steatosis; i148m response

Journal Title: Liver International
Year Published: 2023

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