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Novel cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapies (elexacaftor/tezacaftor/ivacaftor—ETI) promise clinically significant and sustained improvements for patients with cystic fibrosis (CF). In this study, we investigated the impact of… Click to show full abstract
Novel cystic fibrosis transmembrane conductance regulator (CFTR) modulator therapies (elexacaftor/tezacaftor/ivacaftor—ETI) promise clinically significant and sustained improvements for patients with cystic fibrosis (CF). In this study, we investigated the impact of ETI therapy on liver stiffness and bile acid metabolism in a cohort of children and young adults with CF.
Keywords:
acid metabolism;
liver stiffness;
cftr modulator;
fibrosis;
bile acid;
cystic fibrosis
Journal Title: Liver International
Year Published: 2023
Link to full text (if available)
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Journal Title: Liver International
Year Published: 2023
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!