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Ganglioside GD2 Contributes to a Stem‐Like Phenotype in Intrahepatic Cholangiocarcinoma

GD2, a member of the ganglioside (GS) family (sialic acid‐containing glycosphingolipids), is a potential biomarker of cancer stem cells (CSC) in several tumours. However, the possible role of GD2 and… Click to show full abstract

GD2, a member of the ganglioside (GS) family (sialic acid‐containing glycosphingolipids), is a potential biomarker of cancer stem cells (CSC) in several tumours. However, the possible role of GD2 and its biosynthetic enzyme, GD3 synthase (GD3S), in intrahepatic cholangiocarcinoma (iCCA) has not been explored.

Keywords: contributes stem; gd2 contributes; intrahepatic cholangiocarcinoma; ganglioside gd2; gd2

Journal Title: Liver International
Year Published: 2024

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