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Non‐invasive measurement of retinal permeability in a diabetic rat model

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The gold standard for measuring blood‐retinal barrier permeability is the Evans blue assay. However, this technique has limitations in vivo, including non‐specific tissue binding and toxicity. This study describes a… Click to show full abstract

The gold standard for measuring blood‐retinal barrier permeability is the Evans blue assay. However, this technique has limitations in vivo, including non‐specific tissue binding and toxicity. This study describes a non‐toxic, high‐throughput, and cost‐effective alternative technique that minimizes animal usage.

Keywords: invasive measurement; permeability; measurement retinal; non invasive; permeability diabetic; retinal permeability

Journal Title: Microcirculation
Year Published: 2020

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