How oxygen (O2) supply to capillaries is regulated to match the tissue's demand is unknown. Erythrocytes have been proposed as sensors in this regulatory mechanism since they release ATP, a… Click to show full abstract
How oxygen (O2) supply to capillaries is regulated to match the tissue's demand is unknown. Erythrocytes have been proposed as sensors in this regulatory mechanism since they release ATP, a vasodilator, in an oxygen saturation (SO2)‐dependent manner. ATP causes hyperpolarization of endothelial cells resulting in conducted vasodilation to arterioles.
               
Click one of the above tabs to view related content.