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In vitro antidermatophytic synergism of double and triple combination of clioquinol with ciclopirox and terbinafine

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Dermatophytoses are the most frequent fungal infections worldwide and there have been described clinical resistance to the commonly used antifungals. Clioquinol is an antimicrobial that had the oral formulations withdrawn… Click to show full abstract

Dermatophytoses are the most frequent fungal infections worldwide and there have been described clinical resistance to the commonly used antifungals. Clioquinol is an antimicrobial that had the oral formulations withdrawn from the market in the 70s due to the report of neurotoxicity and recently has been considered as an effective alternative for the treatment of dermatophytosis.

Keywords: vitro antidermatophytic; double triple; antidermatophytic synergism; combination clioquinol; synergism double; triple combination

Journal Title: Mycoses
Year Published: 2020

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