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Performance evaluation of fungal DNA PCR amplification from formalin‐fixed paraffin‐embedded tissue for diagnosis: Experience of a tertiary reference laboratory

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Diagnosis of invasive fungal infections from formalin‐fixed paraffin‐embedded (FFPE) tissues by PCR amplification is a developing technology. One of the difficulties of establishing a validated protocol for this testing is… Click to show full abstract

Diagnosis of invasive fungal infections from formalin‐fixed paraffin‐embedded (FFPE) tissues by PCR amplification is a developing technology. One of the difficulties of establishing a validated protocol for this testing is that the gold standard, culture, is much less sensitive than the test being validated.

Keywords: fixed paraffin; pcr amplification; diagnosis; paraffin embedded; formalin fixed

Journal Title: Mycoses
Year Published: 2021

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