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Machine‐learning‐based virtual screening to repurpose drugs for treatment of Candida albicans infection

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Approximately 30% of Candida genus isolates are resistant to all currently available antifungal drugs and it is highly important to develop new treatments. Additionally, many current drugs are toxic and… Click to show full abstract

Approximately 30% of Candida genus isolates are resistant to all currently available antifungal drugs and it is highly important to develop new treatments. Additionally, many current drugs are toxic and cause unwanted side effects. 1,3‐beta‐glucan synthase is an essential enzyme that builds the cell walls of Candida.

Keywords: virtual screening; machine learning; repurpose drugs; based virtual; screening repurpose; learning based

Journal Title: Mycoses
Year Published: 2022

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