Terbinafine is widely used to treat onychomycosis caused by dermatophyte fungi. Terbinafine resistance in recent years is causing concern. Resistance has so far been associated with single‐nucleotide substitutions in the… Click to show full abstract
Terbinafine is widely used to treat onychomycosis caused by dermatophyte fungi. Terbinafine resistance in recent years is causing concern. Resistance has so far been associated with single‐nucleotide substitutions in the DNA sequence of the enzyme squalene epoxidase (SQLE) but how this affects SQLE functionality is not understood.
Keywords:
resistance;
sources resistance;
new sources;
squalene epoxidase;
terbinafine
Journal Title: Mycoses
Year Published: 2024
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Journal Title: Mycoses
Year Published: 2024
Link to full text (if available)
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recommendations!