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Experimental data suggest that systemic immune activation may create a pro‐inflammatory environment with microglia activation in the central nervous system in the absence of overt inflammation, which in turn may… Click to show full abstract
Experimental data suggest that systemic immune activation may create a pro‐inflammatory environment with microglia activation in the central nervous system in the absence of overt inflammation, which in turn may be deleterious in conditions of neurodegenerative disease. The extent to which this is relevant for the human brain is unknown. The central aim of this study is to provide an in‐depth characterization of the microglia and macrophage response to systemic inflammation.
Keywords:
inflammatory activation;
activation microglia;
activation;
microglia brain;
pro inflammatory
Journal Title: Neuropathology and Applied Neurobiology
Year Published: 2019
Link to full text (if available)
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Journal Title: Neuropathology and Applied Neurobiology
Year Published: 2019
Link to full text (if available)
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recommendations!