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Apolipoprotein A‐I (apoA‐I), the principal apolipoprotein associated with high‐density lipoproteins in the periphery, is also found at high concentrations in the cerebrospinal fluid. Previous studies have reported either no impact… Click to show full abstract
Apolipoprotein A‐I (apoA‐I), the principal apolipoprotein associated with high‐density lipoproteins in the periphery, is also found at high concentrations in the cerebrospinal fluid. Previous studies have reported either no impact or vascular‐specific effects of apoA‐I knockout (KO) on β‐amyloid (Aβ) pathology. However, the putative mechanism(s) by which apoA‐I may influence Aβ deposition is unknown.
Keywords:
apolipoprotein decreases;
knockout apolipoprotein;
pathology;
decreases parenchymal;
amyloid pathology
Journal Title: Neuropathology and Applied Neurobiology
Year Published: 2019
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Journal Title: Neuropathology and Applied Neurobiology
Year Published: 2019
Link to full text (if available)
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recommendations!