Desmoplastic infantile astrocytomas and gangliogliomas (DIA/DIGs) are rare brain tumours of infancy. A distinctive feature of their histopathology is a combination of low‐grade and high‐grade features. Most DIA/DIGs can be… Click to show full abstract
Desmoplastic infantile astrocytomas and gangliogliomas (DIA/DIGs) are rare brain tumours of infancy. A distinctive feature of their histopathology is a combination of low‐grade and high‐grade features. Most DIA/DIGs can be surgically resected and have a good prognosis. However, high‐grade features often dominate recurrent tumours, some of which have a poor outcome. In this study, we test the hypothesis that low‐grade and high‐grade areas in DIA/DIGs have distinct molecular characteristics.
               
Click one of the above tabs to view related content.