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Glomerular hyperfiltration in morbid obesity: Role of the inflammasome signalling

Obesity is associated with glomerular hyperfiltration which may precede the development of overt renal damage. Few studies evaluated the link between inflammasome signalling and hyperfiltration. The aim is to evaluate… Click to show full abstract

Obesity is associated with glomerular hyperfiltration which may precede the development of overt renal damage. Few studies evaluated the link between inflammasome signalling and hyperfiltration. The aim is to evaluate the relationship between IL1‐β/Caspase‐1, insulin sensitivity and hyperfiltration in subjects with severe obesity, before and after weight loss.

Keywords: inflammasome signalling; hyperfiltration morbid; glomerular hyperfiltration; morbid obesity; hyperfiltration; obesity

Journal Title: Nephrology
Year Published: 2022

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