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Serum lipopolysaccharide‐binding protein levels and cardiovascular events in hemodialysis patients: A prospective cohort study

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Patients with end‐stage kidney disease (ESKD) exhibit an elevated cardiovascular risk. Chronic inflammation is one of the main mechanisms of cardiovascular disease (CVD). Lipopolysaccharide has been proposed as a link… Click to show full abstract

Patients with end‐stage kidney disease (ESKD) exhibit an elevated cardiovascular risk. Chronic inflammation is one of the main mechanisms of cardiovascular disease (CVD). Lipopolysaccharide has been proposed as a link between systemic inflammation and CVD. Herein, we evaluated whether lipopolysaccharide‐binding protein (LBP), a surrogate marker of lipopolysaccharide and consequent inflammation, is associated with cardiovascular events in ESKD.

Keywords: binding protein; serum lipopolysaccharide; lipopolysaccharide binding; protein levels; cardiovascular events

Journal Title: Nephrology
Year Published: 2022

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