Podocytes, a vital component of the glomerular filtration barrier, are vulnerable to various noxious stimuli, including Hypoxic. HIF1α that transduces hypoxic adaptations induces Transglutaminase 2 (TG2), which catalyses cross‐linking of… Click to show full abstract
Podocytes, a vital component of the glomerular filtration barrier, are vulnerable to various noxious stimuli, including Hypoxic. HIF1α that transduces hypoxic adaptations induces Transglutaminase 2 (TG2), which catalyses cross‐linking of extracellular matrix proteins. In this study, we investigated the mechanism of regulation of TG2 by HIF1α.
Keywords:
hypoxia induced;
metformin prevents;
induced podocyte;
podocyte injury;
prevents hypoxia;
tg2
Journal Title: Nephrology
Year Published: 2022
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Journal Title: Nephrology
Year Published: 2022
Link to full text (if available)
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recommendations!