IgA nephropathy is a mucosally driven disease and new therapeutic approaches are specifically targeting the mucosal production of IgA in the hope that this will lead to a reduction in… Click to show full abstract
IgA nephropathy is a mucosally driven disease and new therapeutic approaches are specifically targeting the mucosal production of IgA in the hope that this will lead to a reduction in circulating IgA immune complexes and mesangial IgA deposition. In this lecture, I discuss the rationale for targeting the mucosal immune system of the gut and the existing data from clinical trials supporting such an approach as a disease modifying treatment for IgA nephropathy.
Keywords:
nephropathy targeting;
mucosal;
mucosal targeting;
targeting iga;
iga nephropathy;
targeting gut
Journal Title: Nephrology
Year Published: 2024
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Journal Title: Nephrology
Year Published: 2024
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!