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Increasing specific immunoglobulin E levels correlate with the risk of anaphylaxis during an oral food challenge

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Oral food challenges (OFCs) are necessary to diagnose food allergies; however, these tests can cause anaphylaxis. Higher specific immunoglobulin E (sIgE) levels to causative food have been associated with a… Click to show full abstract

Oral food challenges (OFCs) are necessary to diagnose food allergies; however, these tests can cause anaphylaxis. Higher specific immunoglobulin E (sIgE) levels to causative food have been associated with a positive OFC. To date, no data have been found to indicate the factors associated with severe symptoms or anaphylaxis among challengeā€positive patients. This study aimed to clarify the association of sIgE with causative foods and anaphylaxis during OFC among the whole study population and challengeā€positive patients.

Keywords: specific immunoglobulin; immunoglobulin levels; food; increasing specific; oral food

Journal Title: Pediatric Allergy and Immunology
Year Published: 2018

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