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Immune‐related microRNAs in breast milk and their relation to regulatory T cells in breastfed children

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The immunomodulatory capacity of breast milk may partially be mediated by microRNAs (miRNA), small RNA molecules that regulate gene expression on a post‐transcriptional level and are hypothesized to be involved… Click to show full abstract

The immunomodulatory capacity of breast milk may partially be mediated by microRNAs (miRNA), small RNA molecules that regulate gene expression on a post‐transcriptional level and are hypothesized to be involved in modulation of immunological pathways. Here, we evaluate the expression of immune‐related miRNAs in breast milk after pre‐ and postnatal supplementation with Limosilactobacillus reuteri and omega‐3 (ω‐3) polyunsaturated fatty acids (PUFAs), and the association to infant regulatory T cell (Treg) frequencies.

Keywords: micrornas breast; related micrornas; immune related; breast milk; milk relation; milk

Journal Title: Pediatric Allergy and Immunology
Year Published: 2023

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