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Delayed concentration effect models for dabigatran anticoagulation

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Dabigatran is an anticoagulant with potential use during cardiopulmonary bypass in children and adults. The pharmacokinetic–pharmacodynamic relationship for dabigatran anticoagulation effect was investigated in an intact animal model using rabbits. Click to show full abstract

Dabigatran is an anticoagulant with potential use during cardiopulmonary bypass in children and adults. The pharmacokinetic–pharmacodynamic relationship for dabigatran anticoagulation effect was investigated in an intact animal model using rabbits.

Keywords: dabigatran anticoagulation; anticoagulation; delayed concentration; effect models; concentration effect

Journal Title: Paediatric Anaesthesia
Year Published: 2022

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