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Endogenous and exogenous opioids are substrates of the permeability glycoprotein (P‐gp) efflux transporter, which is encoded by the ABCB1 (MDR1) gene. Genetic polymorphisms of ABCB1 may contribute to interindividual differences… Click to show full abstract
Endogenous and exogenous opioids are substrates of the permeability glycoprotein (P‐gp) efflux transporter, which is encoded by the ABCB1 (MDR1) gene. Genetic polymorphisms of ABCB1 may contribute to interindividual differences in pain modulation and analgesic responses. We investigated the relationship between ABCB1 polymorphisms and cold pain sensitivity among healthy males.
Keywords:
pain sensitivity;
abcb1 polymorphisms;
sensitivity among;
relationship abcb1;
cold pain;
polymorphisms cold
Journal Title: Pain Practice
Year Published: 2017
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Journal Title: Pain Practice
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!