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Clinical important improvement of chronic pain patients in randomized controlled trials and the DATAPAIN cohort

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Change on the Numeric Rating Scale (NRS) is based on subjective pain experience, hampering the establishment of clinically important improvement. An anchor‐based method, the Patients’ Global Impression of Change (PGIC),… Click to show full abstract

Change on the Numeric Rating Scale (NRS) is based on subjective pain experience, hampering the establishment of clinically important improvement. An anchor‐based method, the Patients’ Global Impression of Change (PGIC), is often added to determine whether a patient has improved. A two‐point change on the NRS has been shown to be equivalent to a moderate clinically important improvement in randomized controlled trials (RCT’s) on medication effects. We contemplated whether these findings could be reproduced in cohort and data and in non‐drug interventional RCT’s.

Keywords: controlled trials; important improvement; clinical important; pain; randomized controlled

Journal Title: Pain Practice
Year Published: 2021

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