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Leukocytopenia in patients treated with multiple antipsychotics, including aripiprazole and quetiapine

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of the DNTC cases studied. However, as you insist, none of our cases have been screened for genetic examinations. When I proposed DNTC, genetic examinations were not as readily available… Click to show full abstract

of the DNTC cases studied. However, as you insist, none of our cases have been screened for genetic examinations. When I proposed DNTC, genetic examinations were not as readily available as they are currently. Now, I support your opinion concerning the importance of genetic examination; however, I am already too old to examine DNTC cases genetically myself. I believe, however, that genetic examination will be performed in Japanese DNTC cases in the near feature. You have cited two papers of cases of idiopathic basal ganglia calcification with SLC20A2 mutation from Japan. I wish to hear from these Japanese authors about those cases in detail. However, these reported cases had neither localized brain atrophy nor pathological NFT findings. Thus, DNTC is quite different from PFBC, although DNTC also shows basal ganglia calcification.

Keywords: leukocytopenia patients; patients treated; dntc; treated multiple; multiple antipsychotics; dntc cases

Journal Title: Psychiatry and Clinical Neurosciences
Year Published: 2017

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