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Disrupting circadian rhythms and sleep disorder have been implicated in the dysregulation of blood glucose and insulin levels and increasing the risk of type 2 diabetes (T2D). Hypothalamic orexin neurons,… Click to show full abstract
Disrupting circadian rhythms and sleep disorder have been implicated in the dysregulation of blood glucose and insulin levels and increasing the risk of type 2 diabetes (T2D). Hypothalamic orexin neurons, which are known to regulate sleep/wake stability, feeding behavior, autonomic nerve activity and energy metabolism, can bidirectionally regulate hepatic gluconeogenesis via control of autonomic balance, leading to generation of the daily blood glucose oscillation and preventing insulin resistance.1
Keywords:
antagonist may;
may regulate;
suvorexant orexin;
orexin antagonist;
serum glucose;
regulate serum
Journal Title: Psychiatry and Clinical Neurosciences
Year Published: 2017
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Journal Title: Psychiatry and Clinical Neurosciences
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!