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High‐power gamma‐related delta phase alteration in schizophrenia patients at rest

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Information processing is supported by the cortico‐cortical transmission of neural oscillations across brain regions. Recent studies have demonstrated that the rhythmic firing of neural populations is not random but is… Click to show full abstract

Information processing is supported by the cortico‐cortical transmission of neural oscillations across brain regions. Recent studies have demonstrated that the rhythmic firing of neural populations is not random but is governed by interactions with other frequency bands. Specifically, the amplitude of gamma‐band oscillations is associated with the phase of lower frequency oscillations in support of short and long‐range communications among networks. This cross‐frequency relation is thought to reflect the temporal coordination of neural communication. While schizophrenia patients show abnormal oscillatory responses across multiple frequencies at rest, it is unclear whether the functional relationships among frequency bands are intact. This study aimed to characterize the lower frequency (delta/theta, 1–8 Hz) phase and the amplitude of gamma oscillations in healthy subjects and schizophrenia patients at rest.

Keywords: frequency; high power; phase; patients rest; schizophrenia patients

Journal Title: Psychiatry and Clinical Neurosciences
Year Published: 2022

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