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Intergenerational concordance of brain structure between depressed mothers and their never‐depressed daughters

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Parents have significant genetic and environmental influences, which are known as intergenerational effects, on the cognition, behavior, and brain of their offspring. These intergenerational effects are observed in patients with… Click to show full abstract

Parents have significant genetic and environmental influences, which are known as intergenerational effects, on the cognition, behavior, and brain of their offspring. These intergenerational effects are observed in patients with mood disorders, with a particularly strong association of depression between mothers and daughters. The main purpose of our study was to investigate female‐specific intergenerational transmission patterns in the human brain among patients with depression and their never‐depressed offspring.

Keywords: intergenerational concordance; brain structure; brain; never depressed; structure depressed; concordance brain

Journal Title: Psychiatry and Clinical Neurosciences
Year Published: 2022

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