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Topical rapamycin (sirolimus) for the treatment of uncomplicated tufted angiomas in two children and review of the literature

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The mTOR inhibitor rapamycin is used systemically for the treatment of vascular lesions. We report the first use of topical rapamycin for the successful treatment of two cases of tufted… Click to show full abstract

The mTOR inhibitor rapamycin is used systemically for the treatment of vascular lesions. We report the first use of topical rapamycin for the successful treatment of two cases of tufted angioma. The evidence for the use of topical rapamycin in other dermatologic conditions is summarized to aid in clinical decision making on preparations and anticipated side effects.

Keywords: topical rapamycin; treatment uncomplicated; rapamycin sirolimus; sirolimus treatment; rapamycin

Journal Title: Pediatric Dermatology
Year Published: 2018

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