LAUSR

An 8yearold boy with prominent venous vessels and hyperlaxity was referred for asssessment of the cutaneous manifestations. He was the second child of consanguineous Moroccan parents, with a past history of cyclic thrombopenia and congenital neutropenia, neonatal sepsis, early-stage chronic renal disease, recurrent aphthous ulcers, and recurrent respiratory tract infections. He also had developmental and neurologic delay from birth, as well as failure to thrive. His past surgical history included repair of an interatrial communication and mitral insufficiency, as well as surgery for cryptorchidism. On physical examination, he had a triangular face, long philtrum, thick lips (Figure 1), aphthous stomatitis (Figure 2), periodontitis, and a prominent venous circulation on his trunk (Figure 3) and extremities.