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Pemphigus and pemphigus‐like reactions can be triggered by a variety of medications including topical therapies, such as imiquimod. While the association between imiquimod and pemphigus‐like reactions has been reported in… Click to show full abstract
Pemphigus and pemphigus‐like reactions can be triggered by a variety of medications including topical therapies, such as imiquimod. While the association between imiquimod and pemphigus‐like reactions has been reported in adults, this is the first report of a generalized reaction beyond the site of imiquimod application in a child. The mechanism by which this occurs may be through a unique pathway, separate from the classic antibody‐mediated pathway. Our patient had a full recovery without recurrence after cessation of the inciting drug.
Journal Title: Pediatric Dermatology
Year Published: 2020
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