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Langerhans cell histiocytosis in children: A retrospective case series of 126 cases

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Langerhans cell histiocytosis (LCH), a rare neoplasm of hematopoietic myeloid precursor cells, is clinically characterized by spontaneously resolving lesions to a progressive life‐threatening multisystem disorder. Diagnosing LCH in children is… Click to show full abstract

Langerhans cell histiocytosis (LCH), a rare neoplasm of hematopoietic myeloid precursor cells, is clinically characterized by spontaneously resolving lesions to a progressive life‐threatening multisystem disorder. Diagnosing LCH in children is challenging as it mimics other skin disorders. This study describes the varied clinical presentation and disease course in children less than 18 years diagnosed with LCH.

Keywords: langerhans cell; histiocytosis children; retrospective case; children retrospective; cell histiocytosis

Journal Title: Pediatric Dermatology
Year Published: 2020

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