LAUSR

, topical preparations, excessive sweating, and occlusion have all been purported triggers. 3 Many of the rare reports of pediatric GP have been linked to the over-treatment of diaper dermatitis with topical products containing zinc oxide. The role zinc oxide plays in the development of GP is unclear, though it is known to speed up epidermal cell turnover resulting in an abnormally thick stratum corneum. 7 There are also reports of children developing GP after exposure to benzalkonium chloride. 7,8 This ammo-nium compound is a skin irritant that can be found in laundry rinses. It is thought to disrupt the lipid bilayers of the epidermis, compromising the process of cornification. 7 In addition, it has been proposed that infants with concomitant atopic dermatitis may be more susceptible to GP since topical products are better able to penetrate the disrupted epidermal barrier of eczematous skin. 9 However, further studies are needed to evaluate the association between infantile GP and atopic dermatitis. Few therapies for pediatric GP