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Citrulline for urea cycle disorders in Japan

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The amino acid l‐citrulline is used as a therapeutic agent for urea cycle disorders (UCD) including ornithine transcarbamylase deficiency (OTCD), carbamoyl phosphate synthetase I deficiency (CPSD), and N‐acetylglutamate synthase deficiency.… Click to show full abstract

The amino acid l‐citrulline is used as a therapeutic agent for urea cycle disorders (UCD) including ornithine transcarbamylase deficiency (OTCD), carbamoyl phosphate synthetase I deficiency (CPSD), and N‐acetylglutamate synthase deficiency. There are few reports, however, on the use of l‐citrulline in Japan and little consensus regarding the effects of l‐citrulline.

Keywords: citrulline urea; cycle disorders; urea cycle; disorders japan; deficiency

Journal Title: Pediatrics International
Year Published: 2017

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