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Increased plasma soluble human leukocyte antigen‐G in persistent wheezy infants

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Human leukocyte antigen (HLA)‐G is a non‐classical major histocompatibility complex class I antigen characterized by limited polymorphism in its coding region, unique tissue expression pattern in physiologic conditions and immunomodulatory… Click to show full abstract

Human leukocyte antigen (HLA)‐G is a non‐classical major histocompatibility complex class I antigen characterized by limited polymorphism in its coding region, unique tissue expression pattern in physiologic conditions and immunomodulatory properties. Recently, the level of soluble (s)HLA‐G was found to be higher in atopic asthma and allergic rhinitis, but this remains to be clarified in wheezy infants. The aim of the present study was therefore to investigate sHLA‐G in wheezy infants.

Keywords: increased plasma; human leukocyte; antigen; wheezy infants; leukocyte antigen

Journal Title: Pediatrics International
Year Published: 2017

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