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Sapropterin hydrochloride, a natural coenzyme (6R‐tetrahydrobiopterin) of phenylalanine hydroxylase, was first approved as a treatment for tetrahydrobiopterin deficiency in 1992 in Japan, and was then approved as a treatment for… Click to show full abstract
Sapropterin hydrochloride, a natural coenzyme (6R‐tetrahydrobiopterin) of phenylalanine hydroxylase, was first approved as a treatment for tetrahydrobiopterin deficiency in 1992 in Japan, and was then approved as a treatment for a tetrahydrobiopterin‐responsive hyperphenylalaninemia in 2007 and 2008, in the USA and Japan, respectively. Guidelines are required on the proper use of sapropterin hydrochloride for tetrahydrobiopterin‐responsive hyperphenylalaninemia.
Keywords:
diagnosis treatment;
treatment;
treatment hyperphenylalaninemia;
guide diagnosis;
hyperphenylalaninemia;
tetrahydrobiopterin
Journal Title: Pediatrics International
Year Published: 2021
Link to full text (if available)
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Journal Title: Pediatrics International
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!