LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

Sulfonylurea for improving neurological features in neonatal diabetes: A systematic review and meta‐analyses

Photo by wrishi2004m from unsplash

In monogenic diabetes due to KCNJ11 and ABCC8 mutations that impair KATP‐ channel function, sulfonylureas improve long‐term glycemic control. Although KATP channels are extensively expressed in the brain, the effect… Click to show full abstract

In monogenic diabetes due to KCNJ11 and ABCC8 mutations that impair KATP‐ channel function, sulfonylureas improve long‐term glycemic control. Although KATP channels are extensively expressed in the brain, the effect of sulfonylureas on neurological function has varied widely. We evaluated published evidence about potential effects of sulfonylureas on neurological features, especially epilepsy, cognition, motor function and muscular tone, visuo‐motor integration, and attention deficits in children and adults with KCNJ11 and ABCC8‐related neonatal‐onset diabetes mellitus.

Keywords: neurological features; improving neurological; features neonatal; sulfonylurea improving; diabetes systematic; neonatal diabetes

Journal Title: Pediatric Diabetes
Year Published: 2022

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.