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Alternative methods for virtual heart transplant—Size matching for pediatric heart transplantation with and without donor medical images available

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Listed pediatric heart transplant patients have the highest solid‐organ waitlist mortality rate. The donor‐recipient body weight (DRBW) ratio is the clinical standard for allograft size matching but may unnecessarily limit… Click to show full abstract

Listed pediatric heart transplant patients have the highest solid‐organ waitlist mortality rate. The donor‐recipient body weight (DRBW) ratio is the clinical standard for allograft size matching but may unnecessarily limit a patient's donor pool. To overcome DRBW ratio limitations, two methods of performing virtual heart transplant fit assessments were developed that account for patient‐specific nuances. Method 1 uses an allograft total cardiac volume (TCV) prediction model informed by patient data wherein a matched allograft 3‐D reconstruction is selected from a virtual library for assessment. Method 2 uses donor images for a direct virtual transplant assessment.

Keywords: heart; pediatric heart; virtual heart; transplant; heart transplant; size matching

Journal Title: Pediatric Transplantation
Year Published: 2018

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