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Antithymocyte globulin (ATG) consists of polyclonal antibodies directed primarily against human T lymphocytes but may contain antibodies with affinity for other tissues in the transplanted organ, resulting in complement (C4d)… Click to show full abstract
Antithymocyte globulin (ATG) consists of polyclonal antibodies directed primarily against human T lymphocytes but may contain antibodies with affinity for other tissues in the transplanted organ, resulting in complement (C4d) deposition. This phenomenon has been demonstrated in endomyocardial biopsies (EMBs) of adult cardiac transplants. We examined the relationship of induction immunosuppression with ATG and C4d deposition in EMB of pediatric cardiac transplants.
Keywords:
deposition;
globulin induction;
transplantation antithymocyte;
antithymocyte globulin
Journal Title: Pediatric Transplantation
Year Published: 2021
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Journal Title: Pediatric Transplantation
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!