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Prospective Evaluation of the Fungitell® (1→3) Beta‐D‐Glucan Assay as a Diagnostic Tool for Invasive Fungal Disease in Pediatric Allogeneic Hematopoietic Cell Transplantation: A Report from the Children's Oncology Group

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Invasive fungal disease (IFD) is a major source of morbidity and mortality for hematopoietic cell transplant (HCT) recipients. Non‐invasive biomarkers, such as the beta‐D‐glucan assay, may improve the diagnosis of… Click to show full abstract

Invasive fungal disease (IFD) is a major source of morbidity and mortality for hematopoietic cell transplant (HCT) recipients. Non‐invasive biomarkers, such as the beta‐D‐glucan assay, may improve the diagnosis of IFD. The objective was to define the utility of surveillance testing using Fungitell® beta‐D‐glucan (BDG) assay in children receiving antifungal prophylaxis in the immediate post‐HCT period.

Keywords: fungal disease; oncology; invasive fungal; glucan assay; hematopoietic cell; beta glucan

Journal Title: Pediatric Transplantation
Year Published: 2022

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