Suspected non‐Alzheimer's disease pathophysiology (SNAP) shows Alzheimer's disease (AD)‐like neurodegeneration; however, amyloid β, which is a biological marker in AD, remains within normal levels. Since the effectiveness of anti‐dementia drugs… Click to show full abstract
Suspected non‐Alzheimer's disease pathophysiology (SNAP) shows Alzheimer's disease (AD)‐like neurodegeneration; however, amyloid β, which is a biological marker in AD, remains within normal levels. Since the effectiveness of anti‐dementia drugs for AD on SNAP is unknown, it is important to distinguish between patients with SNAP and AD. We aimed to compare decreases in regional cerebral blood flow (rCBF) of the posterior cingulate cortex (PCC), precuneus, and parietal lobe critical to AD between SNAP and AD groups using the easy Z‐score imaging system in single‐photon emission computed tomography (eZIS‐SPECT).
               
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