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Effect of OSA on hypoxic and inflammatory markers during CPAP withdrawal: Further evidence from three randomized control trials

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Obstructive sleep apnoea (OSA) is associated with cardiovascular disease. Intermittent hypoxia, endothelial dysfunction and adipose tissue‐mediated inflammation have all been linked to cardiovascular disease in OSA. We therefore explored the… Click to show full abstract

Obstructive sleep apnoea (OSA) is associated with cardiovascular disease. Intermittent hypoxia, endothelial dysfunction and adipose tissue‐mediated inflammation have all been linked to cardiovascular disease in OSA. We therefore explored the effect of OSA on relevant associated blood markers: adrenomedullin (ADM), endocan, endothelin‐1 (ET‐1), resistin and vascular endothelial growth factor (VEGF).

Keywords: effect osa; markers cpap; osa hypoxic; effect; inflammatory markers; hypoxic inflammatory

Journal Title: Respirology
Year Published: 2017

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